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Updated: Jul 22, 2026

Isolating Stem Cells from Soft Musculoskeletal Tissues
Published on: July 5, 2010
The potential of muscle stem cells
P Seale1, A Asakura, M A Rudnicki
1Department of Biology, McMaster University, Hamilton, Ottawa, Canada.
Abstract:
Skeletal muscle contains two types of stem cells: satellite cells, which function as myogenic precursors, and a population of multipotent adult stem cells. Satellite cells are believed to form a stable, self-renewing pool of stem cells in adult muscle where they function in tissue growth and repair. An additional stem cell population in adult muscle displays a remarkable capacity to differentiate into hematopoietic cells as well as muscle following transplantation. This article discusses the characteristics and properties of these cell populations, the relationship between them, and the potential for stem cell-based muscle therapeutics.
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