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Related Experiment Videos

Photoallergic contact dermatitis is uncommon.

A Darvay1, I R White, R J Rycroft

  • 1Department of Environmental Dermatology, St John's Institute of Dermatology, St Thomas' Hospital, Lambeth Palace Road, London SE1 7EH, UK. amritdarvay@doctors.org.uk

The British Journal of Dermatology
|November 13, 2001
PubMed
Summary
This summary is machine-generated.

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Allergic contact (AC) and photoallergic (PA) reactions to UV filters are rare, even with increased sunscreen use. Benzophenone-3 remains a common photoallergen, while others are less frequently used.

Area of Science:

  • Dermatology
  • Photodermatology
  • Contact Dermatitis

Background:

  • Increased sunscreen usage has not led to a rise in allergic contact (AC) and photoallergic (PA) reactions to UV filters.
  • These reactions are considered rare despite widespread sunscreen application.

Purpose of the Study:

  • To analyze data from 2715 patients who underwent photopatch testing between 1983 and 1998.
  • To identify the prevalence and causative agents of AC and PA reactions to UV filters.

Main Methods:

  • Retrospective analysis of positive photopatch test episodes.
  • Data retrieved from environmental dermatology database and verified with original patient records.

Main Results:

  • Out of 2715 patients, 111 (4.1%) had positive reactions; 62 (2.3%) had 80 PA reactions, with UV filters being the most common cause (65%).

Related Experiment Videos

  • Benzophenone-3 was the most frequent UV filter photoallergen (14 reactions), followed by benzophenone-10 (9 reactions).
  • 49 patients (1.8%) experienced 75 AC reactions to UV filters, with benzophenone-10 (13 reactions) and benzophenone-3 (8 reactions) being most common.

    • Conclusions:

    • Photopatch testing shows a low yield of positive reactions, indicating PA reactions to UV filters remain rare.
    • Many previously common UV filter photoallergens are now less used, though benzophenone-3 is still prevalent.
    • Patients with photodermatoses like polymorphic light eruption (PLE) are at higher risk; regular review of photopatch test series is needed as allergen relevance changes.