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Updated: Jul 21, 2026

In Vivo Imaging of Dauer-specific Neuronal Remodeling in C. elegans
Published on: September 4, 2014
Molecular mechanisms of developmental timing in C. elegans and Drosophila
1Howard Hughes Medical Institute, Department of Human Genetics, University of Utah, Salt Lake City 84112, USA. carl.thummel@genetics.utah.edu
Abstract:
Characterization of the heterochronic genes has provided a strong foundation for understanding the molecular mechanisms of developmental timing in C. elegans. In apparent contrast, studies of developmental timing in Drosophila have demonstrated a central role for gene cascades triggered by the steroid hormone ecdysone. In this review, I survey the molecular mechanisms of developmental timing in C. elegans and Drosophila and outline how common regulatory pathways are beginning to emerge.

