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Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Endophthalmitis caused by Moraxella species
A M Berrocal1, I U Scott, D Miller
1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Florida, USA.
American Journal of Ophthalmology
|November 13, 2001
Summary
Moraxella species cause delayed-onset endophthalmitis, often linked to blebs. Despite initial vision loss, good outcomes are common with antibiotic sensitivity, except in complicated cases.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Endophthalmitis is a serious intraocular infection.
- Moraxella species are increasingly recognized as potential pathogens.
Purpose of the Study:
- To determine the incidence and characteristics of endophthalmitis caused by Moraxella species.
- To evaluate antibiotic sensitivities and treatment outcomes.
Main Methods:
- A retrospective case series of patients with Moraxella endophthalmitis treated at Bascom Palmer Eye Institute (1991-2000).
- Review of medical records for clinical presentation, microbiology, and treatment outcomes.
Main Results:
- Moraxella species accounted for 1.3% of bacterial endophthalmitis cases.
- Endophthalmitis was typically delayed-onset, bleb-associated, and presented with severe vision loss.
- Isolates were sensitive to ceftazidime, ciprofloxacin, and aminoglycosides, but resistant to vancomycin.
Conclusions:
- Moraxella endophthalmitis is usually delayed and associated with blebs.
- Good visual outcomes are achievable due to antibiotic sensitivity, barring other ocular complications.
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