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Published on: November 21, 2013
Neuroleptic malignant syndrome in pregnancy
C S Russell1, C Lang, M McCambridge
1Womack Army Medical Center, Fort Bragg, North Carolina 28307, USA. russell@pinehurst.net
Background:
Neuroleptic malignant syndrome can be a serious neurologic complication of drug therapy during pregnancy.
Case:
A young woman was admitted to the intensive care unit with worsening varicella pneumonia. After being given haldol for agitation, she developed fever, increasing agitation, rigidity, tachycardia, and tremors; she was diagnosed as having neuroleptic malignant syndrome. She was treated successfully with bromocriptine and dantrolene.
Conclusion:
Despite the common use of antipsychotic medications, neuroleptic malignant syndrome is seen infrequently during pregnancy. The diagnosis can be difficult to make, but if suspected, it can be treated successfully.
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