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Updated: Aug 14, 2026

Ex Vivo Perfusion of the Rodent Placenta
Published on: May 30, 2019
Placenta percreta with spontaneous rupture of an unscarred uterus in the second trimester
W J LeMaire1, C Louisy, K Dalessandri
1Department of Obstetrics and Gynaecology, St. Jude Hospital, St. Lucia, West Indies, Barbados. wlemaire@mailexcite.com
Background:
Rupture of a pregnant uterus occurs most often in a scarred uterus, and spontaneous rupture of a non-scarred uterus in the early second trimester is rare.
Case:
A woman with two previous normal vaginal deliveries and no prior trauma to the uterus presented at 16 weeks' gestation with an acute abdomen due to intraperitoneal hemorrhage. A large rupture of the fundus of the uterus was found. A supracervical hysterectomy was carried out, with subsequent good recovery. The specimen showed placenta percreta.
Conclusion:
Spontaneous rupture of an unscarred uterus, due to placenta percreta, should be considered in cases of acute intraperitoneal hemorrhage, even in early pregnancy.
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