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Hepatitis B vaccination coverage among United States children
1Health Services Research and Evaluation Branch, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. hay0@cdc.gov
Insights
Hepatitis B vaccine (HepB) coverage in US children has increased significantly since 1991, but has not yet reached the 90% goal. Continued efforts are essential to protect children from this preventable infection.
Area of Science:
- Public Health
- Immunization Practices
- Pediatric Medicine
Background:
- In 1991, universal infant vaccination with three doses of hepatitis B vaccine (HepB) by 18 months was recommended to eliminate transmission in the US.
- Leading pediatric and family physician organizations endorsed similar vaccination schedules.
Purpose of the Study:
- To assess hepatitis B vaccination coverage among young children in the United States.
- To evaluate progress towards national immunization goals.
Main Methods:
- Utilized data from the National Immunization Survey (NIS) conducted quarterly from 1994 onwards.
- Analyzed vaccination status of US children aged 19 to 35 months.
Main Results:
- In 1999, 88.1% of children aged 19-35 months had received at least three doses of HepB (HepB3).
- HepB3 coverage showed a consistent increase since 1994, though the rate of increase slowed.
- Coverage varied by race/ethnicity and state, with 26 states reaching at least 90% HepB3 coverage.
Conclusions:
- Significant progress in HepB vaccination coverage has been made since 1991.
- The 90% coverage target set by the Childhood Immunization Initiative has not yet been achieved.
- Sustained efforts are necessary to ensure protection against hepatitis B infection in US children.
Background:
In 1991 the Advisory Committee on Immunization Practices recommended vaccination of all infants with three doses of hepatitis B virus vaccine (HepB) by 18 months of age as a key component of a comprehensive strategy to eliminate hepatitis B virus transmission in the United States. The American Academy of Pediatrics and the American Academy of Family Physicians published similar recommendations soon afterward.
Methods:
Data were obtained from the National Immunization Survey, a survey that began in 1994 and is conducted quarterly by the Centers for Disease Control and Prevention to estimate vaccination coverage among noninstitutionalized US children 19 to 35 months of age.
Results:
The 1999 National Immunization Survey data indicate that approximately 88.1% (95% confidence interval, 87.4, 88.8) of children 19 to 35 months of age had received at least three doses of HepB (HepB3). There has been a consistent increase in HepB3 coverage since 1994. However, the rate of increase has slowed in recent years and HepB3 coverage remains lower than coverage attained with three doses of diphtheria-tetanus-pertussis and Haemophilus influenzae vaccines. HepB3 coverage varied slightly by race/ethnicity and was highest among white and Asian children (89%). Coverage also varied by state; 26 states had levels of at least 90%.
Conclusions:
Since the 1991 recommendations for universal hepatitis B vaccination, there has been a dramatic increase in coverage levels among children 19 to 35 months of age. However, the Childhood Immunization Initiative goal of 90% coverage has not been reached. Therefore continued efforts are needed to protect US children against this serious but preventable infection.
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