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[Gadolinium-enhanced T(1)-weighted MR urography versus T(2)-weighted (HASTE) MR urography in children]
G Staatz1, C C Nolte-Ernsting, P Haage
1Klinik für Radiologische Diagnostik, Universitätsklinikum der RWTH Aachen. staatz@rad.rwth-aachen.de
Insights
Gadolinium-enhanced MR urography (EMRU) offers superior accuracy for most pediatric urinary tract abnormalities. T(2)-weighted MR urography (HASTE) is best for non-functioning kidneys and cystic diseases, complementing EMRU.
Area of Science:
- Pediatric Radiology
- Urogenital Imaging
- Magnetic Resonance Imaging
Background:
- Upper urinary tract abnormalities are common in children.
- Accurate diagnosis is crucial for appropriate management and outcomes.
- MR urography offers a non-invasive imaging modality for evaluating these conditions.
Purpose of the Study:
- To compare the diagnostic accuracy of gadolinium-enhanced T(1)-weighted excretory MR urography (EMRU) versus T(2)-weighted (HASTE) MR urography.
- To evaluate these techniques in children with various upper urinary tract abnormalities.
Main Methods:
- Prospective study of 63 children (3 weeks to 15 years) using a 1.5-T scanner.
- T(2)-weighted (HASTE) images acquired before and after furosemide.
- Gadolinium-enhanced T(1)-weighted EMRU performed after gadolinium injection using 3D-gradient-echo sequences.
Main Results:
- EMRU showed superior diagnostic accuracy for non-dilated collecting system abnormalities (e.g., horseshoe kidneys, duplex systems).
- Both EMRU and T(2)-weighted MRU were equivalent for assessing obstructed but functioning upper tracts (e.g., UPJ obstructions).
- T(2)-weighted MRU was optimal for visualizing non-functioning dilated collecting systems and multicystic dysplastic kidneys.
Conclusions:
- Respiratory-gated gadolinium-enhanced T(1)-weighted MRU accurately evaluates most pediatric upper urinary tract abnormalities.
- T(2)-weighted (HASTE) MRU serves as a valuable complement to EMRU for assessing non-functioning renal units and cystic kidney diseases.
Purpose:
To evaluate gadolinium-enhanced T(1)-weighted excretory MR urography (EMRU) versus T(2)-weighted (HASTE) MR urography in children with upper urinary tract abnormalities.
Patients And Methods:
In a prospective study 63 children, aged from 3 weeks to 15 years, underwent MR urography in a 1.5-T scanner. Before and after an intravenous injection of 0.05 mg/kg body weight of furosemide, respiratory-triggered HASTE images were obtained for T(2)-weighted MR urography. EMRU was performed subsequent to i. v. gadolinium injection with respiratory-gated, coronal 3 D-gradient-echo sequences.
Results:
Compared to T(2)-weighted (HASTE) MR urography, gadolinium-enhanced MR urography revealed a superior diagnostic accuracy in non-dilated collecting systems (horseshoe kidneys, ectopic kidneys, duplex systems, single ectopic ureters, ureteroceles). EMRU and T(2)-weighted (HASTE) MRU turned out to be equivalent in the assessment of obstructed but normal functioning upper urinary tracts (UPJ obstructions, megaureters). Non-functioning dilated collecting systems and multicystic dysplastic kidneys were best visualized with use of T(2)-weighted (HASTE) MR urography.
Conclusion:
Respiratory-gated gadolinium-enhanced T(1)-weighted MRU allows accurate evaluation of most upper urinary tract abnormalities. T(2)-weighted (HASTE) MRU complements GMRU in the evaluation of non-functioning renal units and cystic disease of the kidneys.
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Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...