Thyrotoxicosis and the heart--a review of the literature
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Published on: August 16, 2016
1Department of Medicine, Obafemi Awolowo University, Ile-Ife, Nigeria.
Insights
Thyroid hormone impacts circulation and heart function. Excess thyroid hormone (thyrotoxicosis) can worsen or cause heart conditions like atrial fibrillation and heart failure, requiring prompt management.
Area of Science:
- Cardiology
- Endocrinology
Background:
- Thyroid hormone influences peripheral circulation and myocardial function.
- Thyrotoxicosis, or excess thyroid hormone, can exacerbate existing cardiac conditions or induce new ones.
Purpose of the Study:
- To raise awareness of cardiac complications associated with thyrotoxicosis in Nigeria.
- To highlight the importance of recognizing cardiac issues like atrial fibrillation and heart failure in thyrotoxicosis patients.
Main Methods:
- Review of cardiac effects of thyroid hormone.
- Observation of increasing thyrotoxicosis cases in Nigeria.
- Discussion of diagnostic and treatment facility improvements.
Main Results:
- Thyrotoxicosis can lead to significant cardiac problems, including atrial fibrillation and cardiac failure.
- Increased reporting of thyrotoxicosis in Nigeria correlates with improved healthcare access.
Conclusions:
- Greater awareness of thyrotoxicosis-related cardiac disease is needed in Nigeria.
- Management involves prompt treatment of hyperthyroidism alongside diuretics, digoxin, and beta-blockers.
Abstract:
Thyroid hormone has effects on both the peripheral circulation and the myocardium. These include a decline in the systemic vascular resistance and an increase in cardiac output and cardiac contractility. Exposure to excess thyroid hormone, as occurs in thyrotoxicosis, can not only aggravate preexisting cardiac disease but also by itself lead to cardiac disease. More patients are being reported with thyrotoxicosis in Nigeria while the facilities for diagnosis and treatment are improving and becoming more available. There should therefore be a greater awareness of the cardiac problems associated with thyrotoxicosis, especially atrial fibrillation and cardiac failure. Initial management of heart disease in thyrotoxicosis should focus on the prompt alleviation of hyperthyroidism combined with judicious use of diuretics, digoxin and beta-blockers.
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