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Related Experiment Videos

Health economic guidelines--similarities, differences and some implications.

J Hjelmgren1, F Berggren, F Andersson

  • 1AstraZeneca R & D Lund, Clinical Science, Health Economics & Outcomes Research, SE-221 87 Lund, Sweden.

Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research
|November 14, 2001
PubMed
Summary

Health economic guidelines from Europe, North America, and Australia show significant harmonization. Despite some differences in methodology, a core agreement exists, impacting pharmaceutical industry policy.

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Area of Science:

  • Health Economics
  • Health Policy
  • Guideline Development

Background:

  • Health economic (HE) guidelines are crucial for decision-making in healthcare.
  • Variations in HE guidelines across regions can impact policy and industry practices.
  • A comprehensive comparison of existing guidelines is needed to identify commonalities and divergences.

Purpose of the Study:

  • To classify, summarize, and compare health economic guidelines from Europe, North America, and Australia.
  • To identify similarities and differences in methodological approaches across these regions.
  • To inform harmonization efforts and policy development.

Main Methods:

  • A literature review was conducted to identify relevant health economic guidelines.
  • Guidelines were categorized into formalized, informal, and those for HE methods.

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  • Fifteen key methodological aspects were extracted and compared within and between guideline groups.

    • Main Results:

    • Twenty-five guidelines were analyzed: seven formalized, eight informal, and ten for HE methods.
    • High levels of agreement were observed within and between guideline groups, particularly for formalized guidelines.
    • Disagreements were noted in the choice of perspective, included resources/costs, and evaluation methods for resources.

    Conclusions:

    • A substantial harmonization of methodological requirements exists within and between guideline groups.
    • This review highlights areas of consensus in health economic guideline development.
    • Identified policy implications are particularly relevant for the pharmaceutical industry.