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Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs
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Published on: April 21, 2012

Evaluation of the efficacy of two leishmanins in asymptomatic dogs

L Solano-Gallego1, J Llull, M Arboix

  • 1Facultat de Veterinària, Departament de Farmacologia i de Terapèutica, Universitat Autònoma de Barcelona, Edifici V, Bellaterra, E-08193 Barcelona, Spain. lsolano@quiro.uab.es

Veterinary Parasitology
|November 14, 2001
PubMed

There are few studies in dogs concerning leishmanin skin test. We evaluated and compared the efficacy of two leishmanin preparations for the detection of dog Leishmania cellular-mediated immunity. Clinically healthy dogs living in an endemic area were studied. A leishmanin preparation 1 (3 x 10(8) promastigotes/ml) was superior to a leishmanin preparation 2 (5 x 10(6) promastigotes/ml), measured as the percentage of positive reactions and the diameter of the induced induration. The leishmanin skin test is a valuable tool, although the results show that the degree of response, as it has been shown in human beings, depends on the preparation used.

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