Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Future directions for epilepsy research.

M P Jacobs1, G D Fischbach, M R Davis

  • 1National Institute of Neurological Disorders and Stroke, NIH, Rockville, MD 20892, USA.

Neurology
|November 14, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Open-Label Allopregnanolone Treatment of Men with Fragile X-Associated Tremor/Ataxia Syndrome.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics·2017
Same author

Ankyrin-G isoform imbalance and interneuronopathy link epilepsy and bipolar disorder.

Molecular psychiatry·2016
Same author

Proconvulsant actions of intrahippocampal botulinum neurotoxin B in the rat.

Neuroscience·2013
Same author

AMPA receptors as a molecular target in epilepsy therapy.

Acta neurologica Scandinavica. Supplementum·2013
Same author

Preclinical pharmacology of perampanel, a selective non-competitive AMPA receptor antagonist.

Acta neurologica Scandinavica. Supplementum·2013
Same author

Abbreviated report of the NIH/NINDS workshop on sudden unexpected death in epilepsy.

Neurology·2011
Same journal

Spatiotemporal Associations Between Cortical Microinfarcts and Cortical Superficial Siderosis in Cerebral Amyloid Angiopathy.

Neurology·2026
Same journal

Blood-Brain Barrier Disruption Before Interhospital Transfer for Thrombectomy and Clinical Outcome.

Neurology·2026
Same journal

At Death's Door: Cytosolic Dopamine in Patients With Parkinson Disease.

Neurology·2026
Same journal

Cerebral Artery Pulsatility, Premorbid Blood Pressure, and Small Vessel Disease on Brain Imaging: A Population-Based Study.

Neurology·2026
Same journal

Genetic Risk for Alzheimer Disease, Midlife Hypertension, and Dementia: The ARIC Neurocognitive Study.

Neurology·2026
Same journal

What is the Relevance of Neuron-Tumor Interactions in Malignant CNS Tumors?

Neurology·2026
See all related articles

Epilepsy research should shift from symptom management to prevention and cures. Advances in genetics, brain imaging, and seizure prediction enable new therapeutic strategies for epilepsy.

Area of Science:

  • Neuroscience
  • Genetics
  • Medical Research

Background:

  • Current epilepsy research primarily focuses on symptom control.
  • Recent scientific advancements provide opportunities for a paradigm shift.

Purpose of the Study:

  • To propose a revitalized research agenda for epilepsy.
  • To shift focus from symptom management to prevention and cure.

Main Methods:

  • Leveraging advances in genetic identification of epilepsy syndromes.
  • Utilizing molecular characterization of brain networks.
  • Employing advanced neuroimaging and quantitative electroencephalography (EEG) for seizure prediction.

Main Results:

  • Identification of genes associated with inherited epilepsy syndromes.

Related Experiment Videos

  • Improved understanding of brain network molecular characteristics.
  • Enhanced capabilities in imaging seizure origins and predicting seizures via EEG analysis.

    • Conclusions:

    • A shift towards epilepsy prevention and cure is feasible.
    • Future research should explore epilepsy development mechanisms and genetic underpinnings.
    • Therapeutic directions include novel molecular targets, advanced drug delivery, gene/cell therapy, and integrated imaging-electrophysiology approaches.