Use of thalidomide in HIV infection

Despite its disastrous past, thalidomide has reentered the medical community. This article reviews available evidence for its potential application to the treatment of some complications of HIV infection. HIV-related conditions in which thalidomide may be useful include aphthous ulcers, wasting, diarrhea, and nodular prurigo. Vigilance must be maintained to minimize adverse effects and prevent fetal exposure.