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Detection of Low Copy Number Integrated Viral DNA Formed by In Vitro Hepatitis B Infection
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Hepatitis B virus nucleic acids circulating in the blood: distinct patterns in HBs carriers with hepatocellular

R Breitkreutz1, W Zhang, M Lee

  • 1Department of Virus-Host Interactions, Deutsches Krebsforschungszentrum, Heidelberg, Germany.

Annals of the New York Academy of Sciences
|November 16, 2001
PubMed

Circulating nucleic acids in serum and plasma are common in a variety of disease conditions. Here, we focus (i) on our approach for the detection of various hepatitis B virus (HBV)-related nucleic acids in liver tissue and in serum, (ii) on the progression of the chronic HBV infection, (iii) on the relation of HBV-specific nucleic acids circulating in the blood of patients with hepatocellular carcinoma, and in general (iv) on the diagnostic potential of circulating HBV nucleic acids.

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