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Updated: Aug 2, 2026

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Published on: January 14, 2018
Migration through host cells by apicomplexan parasites
1Department of Pathology, New York University, 550 First Avenue, New York, NY 10016, USA.
Abstract:
In what appears to be an essential prelude to establish a successful infection in the mammalian host, Plasmodium sporozoites move rapidly through several host cells breaching the cell plasma membranes in the process. This mode of invasion precedes the 'traditional' mode in which the sporozoite enters by invagination of the host cell membrane and develops within a parasitophorous vacuole. Here we revisit the existing literature that supports the presence of similar invasive behaviors in other apicomplexan parasites.
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