Related Experiment Video
Updated: Oct 3, 2026
A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Endometrial metastasis of cutaneous melanoma - A case-report bearing diagnostic difficulties -
J Heinig1, C August, V Beckmann
1Department of Obstetrics and Gynaecology, University of Münster, Germany.
Objective:
To report a rare case of endometrial metastasis of cutaneous malignant melanoma, mimicked by histologically xanthomatous lesion. Only about ten other cases of endometrial metastasis of this malignancy have been reported previously. -
Design:
Case report. -
Patient:
A 60 year old female. -
Main Outcome Measure:
Fractionated curettage and immunohistologically examination of the tissue. -
Results:
Due to xanthomatous regressive changes of the metastatic tissue, difficulties in the histological confirmation as a metastasis of an unpigmented malignant melanoma occurred. But immunohistological staining showed positivity for S-100 and MART-1, as did the primary tumour. -
Conclusions:
If atypical bleeding in patients with known malignant melanoma of the skin occur endometrial metastasis should be excluded by gynaecologists.
