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A flavone glycoside from Andrographis alata
A G. Damu1, B Jayaprakasam, K V. Rao
1Natural Products Division, Department of Chemistry, Sri Venkateswara University, -517 502, Tirupati, India
Phytochemistry
|November 17, 2001
Summary
Researchers isolated a new compound, echioidinin 5-glucoside, and its known aglycone from the Andrographis alata plant. The new compound
Area of Science:
- Phytochemistry
- Natural Product Chemistry
- Medicinal Botany
Background:
- Andrographis alata is a plant with potential medicinal properties.
- Flavonoids are a class of natural compounds with diverse biological activities.
Purpose of the Study:
- To isolate and characterize new compounds from Andrographis alata.
- To elucidate the chemical structure of isolated compounds.
Main Methods:
- Phytochemical analysis of the whole Andrographis alata plant.
- Spectroscopic studies (e.g., NMR, Mass Spectrometry) for structure elucidation.
- Chemical methods for structural confirmation.
Main Results:
- Isolation of a novel flavone glycoside, echioidinin 5-glucoside.
- Isolation of the known aglycone, echioidinin.
- Structural determination of echioidinin 5-glucoside as 5,2'-dihydroxy-7-methoxyflavone 5-O-beta-D-glucopyranoside.
Conclusions:
- A new flavone glycoside, echioidinin 5-glucoside, has been identified in Andrographis alata.
- The structural elucidation provides valuable data for further research into the bioactivity of this compound.