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Syntheses and biological evaluation of alkanediamines as antioxidant and hypolipidemic agents
S Batra1, A P Bhaduri, B S Joshi
1Medicinal Chemistry Division, Central Drug Research Institute, Lucknow 226 001, India. batra_san@yahoo.co.uk
Abstract:
A new series of compounds belonging to N,N'- [bis (1-aryl-6-hydroxy-hex-2-ene-1-one-3-yl)-1,n-alkanediamines (2-5a-f) have been synthesized and evaluated for antioxidant and hypolipidemic activities. Amongst all the synthesized compounds, seven compounds namely 2c, 2e, 4c, 5b, 5c, 5e and 5f exhibit potent antioxidant activity. These compounds have also been evaluated for hypolipidemic activity.
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