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[Cystic mesothelioma of the greater omentum]
Abstract:
Peritoneal cystic mesothelioma is very rare clinical entity, and only a few cases situated on the greater omentum are described. The authors here presented two cases of the greater omentum cystic mesothelioma that were diagnosed in 260,000 adult patients hospitalized for the first time, during the fifteen year period. Cystic tumor of 30 cm in diameter was found in a 78 years old male patient, and the second one was 35 cm in diameter in female patient 56 years old. Symptomatology was not characteristic. Peritoneal pseudocyst or parasitic, lymphogen, urogenital, enteric or dermoid cyst origin was preoperatively excluded, and correct diagnosis was established upon the operative findings and immuno-histochemical investigations. In both cases keratin and vimentin were clearly positive in tumor cells, but other markers were negative (EMA, Actin, S-100, NSE, chromogranin and sinoptophysin). Cystic mesothelioma was not infiltrative and surgical treatment was simple and successful.
Insights
Peritoneal cystic mesothelioma is a rare tumor. This study presents two large cases found in the greater omentum, highlighting successful surgical outcomes.
Area of Science:
- Oncology
- Gastroenterology
- Pathology
Background:
- Peritoneal cystic mesothelioma is an exceptionally rare neoplasm.
- Cases involving the greater omentum are particularly scarce in medical literature.
Observation:
- Two adult patients presented with large cystic tumors (30 cm and 35 cm) in the greater omentum.
- Preoperative differential diagnosis excluded other cystic origins, including pseudocysts and parasitic cysts.
- Clinical presentation lacked specific characteristic symptoms.
Findings:
- Diagnosis was confirmed through operative findings and immunohistochemical analysis.
- Tumor cells showed positive staining for keratin and vimentin.
- Other markers such as EMA, Actin, S-100, NSE, chromogranin, and synaptophysin were negative.
Implications:
- Cystic mesothelioma of the greater omentum, though rare, is a distinct entity.
- Non-infiltrative nature suggests favorable prognosis.
- Simple surgical excision proved effective in these cases, indicating a potentially straightforward treatment approach.
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