Contact mechanics of a thin-walled capsule adhered onto a rigid planar substrate

A thin-walled capsule, modelled as an incompressible liquid droplet contained in a thin flexible membrane, was allowed to adhere onto a rigid substrate. The contact mechanics were formulated, based on linear elasticity, to portray quantitatively the relationships between osmotic inflation, contact area and angle, membrane stretching and adhesion strength. The predicted results shed light on fundamental adhesive contact mechanics in a cell-substrate system.