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Updated: Aug 19, 2026

A High-throughput Method for Measurement of Glomerular Filtration Rate in Conscious Mice
Published on: May 10, 2013
[Comparison of methods for the determination of blood creatinine]
A M Hanser1, B Hym, O Michotey
1Laboratoire de biochimie, Centre hospitalier, 68024 Colmar, France.
Abstract:
Creatinine is the criterion the most widely used for kidney exploration, either directly or through algorithms. Up to now, it appears that methods of creatinine determination are still very heterogenous. The aim of the present study was to compare the different available methods and to evaluate their impact on the formula of predicted clearance. The study revealed that significant discrepancies can be observed depending on the methodology and analitycal principe. The results suggest that standardization of methods and comprehensive analysis of the different formula are necessary.
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