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Late opacification of the foldable hydrophilic acrylic lens SC60B-OUV
A Frohn1, H B Dick, A J Augustin
1University Eye Hospital Tuebingen, Tuebingen, Germany. andreas.frohn@t-online.de
Objective:
To investigate the cause of severe central opacification in 41 foldable acrylic intraocular lenses (IOLs) requiring explantation. Another IOL was opacified in the original sealed vial.
Design:
Case series and laboratory analysis.
Testing:
Light microscopy, high performance liquid chromatography, sodium dodecyl sulfate polyacoylamide gel electrophoresis, spectrometric analysis, and autoclaving.
Results:
Neither fatty acids nor proteins could be identified within the IOLs. Spectrometric analysis yielded absorption peaks in the ultraviolet spectral range.
Conclusions:
The spectroscopic findings indicate premature aging of the ultraviolet blocking agent. The source of the opacification is a change in the IOL material itself.