Related Experiment Video
Updated: Oct 3, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Treatment of an orchiectomized patient with hormone-refractory prostate cancer with LH-RH agonists
C Damyanov1, B Tzingilev, V Tabakov
1National Oncology Center, Sofia, Bulgaria. damianov@bgnet.bg
Abstract:
This report confirms experimental data on direct inhibitory effects of LH-RH agonists in growth control of human prostate cancer cells. The patient had hormone-refractory prostatic carcinoma after hormonal therapy, including orchiectomy, and responded successfully to a 6-month treatment with goserelin acetate (3.6 mg depot s.c.). The treatment has led to a reduction of tumor mass and metastases as well as an improvement in the patient's paraclinical indicators and general status. The remission lasted 14 months. The treatment still continues.
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