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Minimally invasive application of botulinum toxin type A in nasal hypersecretion
1Department of Otorhinolaryngology, Head and Neck Surgery, Georg August University, Robert-Koch-Strasse 40, D-37075 Göttingen, Germany. saskia.rohrbach@med.uni-goettingen.de
Abstract:
We report on the effect of the local application of botulinum toxin A on nasal hypersecretion in a female patient with intrinsic rhinitis. 20 units of botulinum toxin A (Botox) was inserted into each nostril using a small sponge in close contact with the lower and middle turbinates. The effect was scored by the patient and by rhinomanometry. Nasal hypersecretion diminished clearly 5 days after the treatment. The rhinomanometric flow increased 2 weeks after the application. No side effects occurred. We conclude that this minimal invasive method of local botulinum toxin application might be a very effective and safe option for the treatment of nasal hypersecretion of different etiologies.