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Updated: Aug 9, 2026

Experimental Human Pneumococcal Carriage
Published on: February 15, 2013
Eleven-year study of recurrent pneumococcal bacteremia
B Font1, C Llimiñana, D Fontanals
1Internal Medicine Department, Corporació Parc Taulí, Barcelona, Spain. bfont@cspt.es
Recurrent pneumococcal bacteremia is rare, affecting 3.9% of patients. Hematological neoplasia is the only identified risk factor for these reinfections, highlighting the need for targeted prevention strategies.
Area of Science:
- Infectious Diseases
- Epidemiology
- Microbiology
Background:
- Pneumococcal bacteremia is a significant cause of bloodstream infections.
- Understanding recurrent episodes is crucial for patient management and public health.
Purpose of the Study:
- To describe the epidemiology of recurrent pneumococcal bacteremia.
- To detail the clinical and microbiological features of recurrent pneumococcal bacteremia.
Main Methods:
- A long-term study was conducted between January 1988 and December 1998.
- Epidemiological data and microbiological findings from 344 episodes in 331 patients were analyzed.
- Pulsed-field techniques were used to compare bacterial strains.
Main Results:
- Thirteen patients (3.9%) experienced recurrent pneumococcal bacteremia, all with underlying diseases.
- Recurrence was attributed to reinfection in 12 patients and relapse in one.
- Identical strains were identified in three patients with recurrent episodes.
- Hematological neoplasia was the sole identified predisposing factor.
Conclusions:
- Recurrent pneumococcal bacteremia is uncommon and primarily linked to underlying conditions.
- Hematological neoplasia is a significant risk factor for recurrent pneumococcal infections.
- Further research into prevention and management strategies for high-risk individuals is warranted.
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