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Updated: Jul 22, 2026

Murine Model of Allergen Induced Asthma
Published on: May 14, 2012
Risk factors for asthma prevalence among urban and nonurban African American children
J von Maffei1, W S Beckett, K Belanger
1Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, USA.
Insights
Urban living increases asthma risk in African American children. However, factors like maternal asthma, smoking, and home environment are more significant than urban residence alone.
Area of Science:
- Environmental Health
- Pediatric Asthma Research
- Epidemiology
Background:
- Urban residence is a known risk factor for childhood asthma.
- Identifying specific contributing factors is crucial for effective prevention strategies.
Purpose of the Study:
- To examine multiple risk factors for asthma simultaneously in African American children.
- To determine if urban residence remains a significant risk factor after accounting for other variables.
Main Methods:
- Survey of 2409 African American mothers with at least one child under 18.
- Assessed prevalence of physician-diagnosed asthma and various potential risk factors.
- Statistical analysis to identify significant associations.
Main Results:
- Sixteen percent of children had physician-diagnosed asthma.
- Maternal asthma/allergies, maternal smoking, humidifying devices, and gas ranges were significantly associated with childhood asthma.
- Urban residence was initially related but lost significance when other factors were controlled.
Conclusions:
- Asthma in urban African American children is linked to specific, identifiable factors.
- Environmental and familial factors within the home play a critical role in asthma development.
- Public health interventions should focus on these modifiable risk factors.
Abstract:
Urban residence is a risk factor for asthma. We examined multiple risk factors simultaneously among African American children. We interviewed 2409 African American mothers of newborns who had at least 1 child at home under 18 years of age. Sixteen percent reported at least 1 child with physician-diagnosed asthma. Significantly associated with an asthmatic child were maternal asthma and allergies, maternal cigarette smoking, a humidifying device, and a gas range or oven in the home. Urban residence was related to asthma but became nonsignificant once other factors were controlled for. Asthma associated with urban residence may be explained by identifiable factors.
Related Concept Videos
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-I: Introduction
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma-III: Symptoms and Complications
Classification of Asthma
Asthma I: Introduction
Chronic Obstructive Pulmonary Disease I: Introduction

