Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cost-effective gel documentation using a web-cam.

T Goldmann1, A Zyzik, S Loeschke

  • 1Clinical and Experimental Pathology, Research Center Borstel, Parkallee 1-40, D-23845 Borstel, Germany. tgoldmann@fz-borstel.de

Journal of Biochemical and Biophysical Methods
|November 21, 2001
PubMed
Summary

A low-cost webcam can document DNA gels for molecular biology research. This system offers affordable gel imaging, combining low setup and running costs for routine documentation needs.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Molecular pathology of tuberculosis : Status, methodology, and limits].

Der Pathologe·2021
Same author

Meat allergy associated with galactosyl-α-(1,3)-galactose (α-Gal)-Closing diagnostic gaps by anti-α-Gal IgE immune profiling.

Allergy·2017
Same author

PD-L1 copy number gain in nonsmall-cell lung cancer defines a new subset of patients for anti PD-L1 therapy.

Annals of oncology : official journal of the European Society for Medical Oncology·2015
Same author

Improved diagnostics targeting c-MET in non-small cell lung cancer: expression, amplification and activation?

Diagnostic pathology·2015
Same author

[A reduced TKI dosage is not associated with loss of activity in EGFR mutated NSCLC patients].

Pneumologie (Stuttgart, Germany)·2014
Same author

Transforming growth factor-beta signaling leads to uPA/PAI-1 activation and metastasis: a study on human breast cancer tissues.

Pathology oncology research : POR·2014

Area of Science:

  • Molecular Biology
  • Biotechnology
  • Biochemistry

Background:

  • Gel documentation systems are crucial for molecular biology.
  • Existing systems can be expensive, limiting accessibility.
  • There is a need for cost-effective gel imaging solutions.

Purpose of the Study:

  • To evaluate a low-cost webcam for DNA gel documentation.
  • To assess its suitability for routine molecular biology applications.
  • To compare its cost-effectiveness against traditional systems.

Main Methods:

  • A webcam connected to a personal computer via USB was used.
  • Agarose gels with DNA stained by ethidium bromide were imaged.
  • Standard webcam software was utilized for image capture.

Related Experiment Videos

Main Results:

  • The webcam produced digital images of sufficient quality for routine gel documentation.
  • The system demonstrated low setup costs, similar to Polaroid systems.
  • Running costs were comparable to video capture systems.

Conclusions:

  • Webcams offer a cost-effective solution for DNA gel documentation.
  • This approach is ideal for startup laboratories and augmenting existing equipment.
  • It provides a viable alternative for routine molecular biology imaging needs.