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[Truss-induced macular amyloidosis].

C Abels1, S Karrer, M Landthaler

  • 1Klinik und Poliklinik für Dermatologie, Klinikum der Universität Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg. christoph.abels@klinik.uni-regensburg.de

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|November 22, 2001
PubMed
Summary

Localized macular amyloidosis, a skin condition, was diagnosed in an 80-year-old male due to chronic friction from a hernia truss. This highlights friction as a potential cause, avoiding unnecessary systemic amyloidosis workups.

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Area of Science:

  • Dermatology
  • Pathology

Background:

  • Amyloidosis is characterized by amyloid protein deposits in organs or tissues.
  • Localized cutaneous amyloidoses present as skin lesions, often requiring differentiation from systemic forms.

Observation:

  • An 80-year-old male presented with a chronic, localized red-brown macule with lichenification in the right groin.
  • Initial biopsy showed amyloid deposits, prompting a systemic workup for amyloidosis, which yielded nonspecific results.
  • A subsequent skin biopsy revealed epidermal changes and eosinophilic deposits in the dermis, positive for thioflavine.

Findings:

  • The skin lesion's location corresponded to a right inguinal hernia truss worn by the patient.
  • The diagnosis of localized macular amyloidosis was confirmed, likely caused by persistent local friction.

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  • Systemic workup, including rectal biopsy, did not reveal evidence of systemic amyloidosis.

    • Implications:

    • This case suggests that chronic local friction, such as from a hernia truss, can cause localized macular amyloidosis.
    • Including local trauma as a cause in the classification of localized cutaneous amyloidoses may prevent unnecessary systemic investigations.
    • Accurate diagnosis based on clinical presentation and biopsy findings is crucial for appropriate patient management.