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[Apoptosis induced by ionizing radiation in TCC cell lines, EJ and BIU-87]
Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]
|November 22, 2001
Abstract
Objective:
To study the effect of ionizing radiation on the living status of TCC cell lines, EJ and BIU-87.
Methods:
Different doses of X-ray were used on cell lines, EJ and BIU-87, and the cells were observed microscopically by fluorescent staining(EB and AO).
Results:
The number of normal living cells declined and apoptotic as well as necrotic cells elevated with increase of radiation doses except for doses equal to or below 100 cGY, Apoptotic and necrotic cells increased as postradiation time delayed.
Conclusion:
The ionizing radiation may induce TCC apoptosis and necrosis.