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Related Experiment Videos

Tinea capitis update: a continuing conflict with an old adversary.

B K Chen1, S F Friedlander

  • 1Pediatric and Adolescent Dermatology, Children's Hospital, San Diego, California, USA.

Current Opinion in Pediatrics
|November 22, 2001
PubMed
Summary

Tinea capitis infections in children are increasing, especially in African-Americans, with the common fungus Trichophyton tonsurans. Current treatments like griseofulvin show decreased effectiveness, prompting research into new antifungal medications.

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Area of Science:

  • Dermatology
  • Mycology
  • Infectious Diseases

Background:

  • Tinea capitis is a prevalent childhood fungal infection with evolving epidemiology.
  • Trichophyton tonsurans is the predominant cause in the United States.
  • Recent trends show a significant rise in tinea capitis incidence, particularly among African-American children.

Purpose of the Study:

  • To review the changing epidemiology of tinea capitis.
  • To assess the current treatment efficacy of griseofulvin.
  • To highlight advancements in diagnosis and novel therapeutic agents.

Main Methods:

  • Review of recent epidemiologic data on tinea capitis.
  • Analysis of clinical studies on griseofulvin treatment response.
  • Evaluation of emerging diagnostic techniques and new antifungal drugs.

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Main Results:

  • Trichophyton tonsurans is the leading cause of childhood tinea capitis in the US.
  • A notable increase in tinea capitis cases among African-Americans has been observed.
  • Decreased sensitivity to griseofulvin is suggested in recent clinical studies.

Conclusions:

  • The changing epidemiology of tinea capitis necessitates updated treatment strategies.
  • Newer antifungal medications like terbinafine, itraconazole, and fluconazole show promise.
  • Improved diagnostic methods, such as the cotton swab technique, are being re-emphasized.