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Updated: Oct 3, 2026

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation
Published on: February 29, 2020
[The diagnosis and treatment of cerebrospinal fluid rhinorrhea]
1Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730.
Objective:
To summarize our experience in managing cerebrospinal fluid(CSF) rhinorrhea.
Methods:
Twenty-nine cases with cerebrospinal fluid rhinorrhea from 1982 to March of 1997 were reviewed. The duration of CSF rhinorrhea varied from 3 months to 23 years. The ages of the patients ranged from 7 to 72 years.
Results:
The causes of CSF leak were spontaneous in 18 cases, traumatic in 6 (1 had two accidents and got two different leaking sites) and iatrogenic in 5 cases. Twenty-two cases underwent surgical repair. Overall closure rate was 81.8%. The causes, symptoms and signs, sites of leakage and surgical techniques were analyzed. The classification, diagnosis and treatment of CSF rhinorrhea were discussed.
Conclusion:
Transnasal extracranial repair undertaken by otorhinolaryngologist got better closure rate(93.8%) in this group. Transnasal endoscopic repair could afford excellent view, facilitate precise tissue graft placement and get better closure rate.
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