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Bladder adenocarcinoma: 31 reported cases
L Xiaoxu1, L Jianhong, W Jinfeng
1Department of Urology, The Second Affiliated Hospital of Shanxi Medical University, Taiyuan, 030001 Shanxi, P.R. of China.
The Canadian Journal of Urology
|November 24, 2001
Summary
This study compared primary bladder adenocarcinoma with urachal adenocarcinoma, finding the latter affects younger females and has poorer survival. Partial cystectomy for bladder adenocarcinoma showed a high local recurrence rate.
Area of Science:
- Urology
- Oncology
Background:
- Bladder adenocarcinoma is a rare malignancy.
- Urachal adenocarcinoma is a subtype with distinct characteristics.
Purpose of the Study:
- To compare clinical features and outcomes of primary bladder adenocarcinoma and urachal adenocarcinoma.
- To evaluate the efficacy of different surgical approaches for bladder adenocarcinoma.
Main Methods:
- Retrospective review of 31 patients diagnosed between 1985-1999.
- Analysis included patient demographics, tumor type, treatment, and survival rates.
Main Results:
- Urachal adenocarcinoma (6 patients) occurred in younger individuals (56 years) with female predominance (1:2 M:F) and worse 3-year survival (20%) compared to primary bladder adenocarcinoma (56 years, 3:1 M:F, 45% survival).
- For primary bladder adenocarcinoma, 3-year survival was 45% after radical cystectomy and 33% after partial cystectomy.
- Local tumor recurrence after partial cystectomy was 25%.
Conclusions:
- Urachal adenocarcinoma presents differently than primary bladder adenocarcinoma, affecting younger females and showing poorer survival.
- Partial cystectomy for bladder adenocarcinoma is linked to a significant rate of local recurrence.