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Anthrax: a motor protein determines anthrax susceptibility
1Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA. Pchanna@umich.edu
Current Biology : CB
|November 24, 2001
Abstract:
A new study has found that polymorphisms in the host gene kif1C, which encodes a kinesin-like motor protein, determine whether mouse macrophages are resistant or sensitive to anthrax lethal toxin. These findings may lead the way to discovering how both germ and host factors might contribute to a lethal infection.