Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dedicated breast CT: radiation dose and image quality evaluation.

J M Boone1, T R Nelson, K K Lindfors

  • 1Department of Radiology, X-ray Imaging Laboratory, University of California, Davis Medical Center, 4701 X St, Sacramento, CA 95817, USA. jmboone@ucdavis.edu

Radiology
|November 24, 2001
PubMed
Summary

Dedicated breast computed tomography (CT) shows potential for cancer screening. Radiation doses are comparable to mammography, with superior image quality, especially for denser breasts.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

GEANT4 Monte Carlo simulations for virtual clinical trials in breast X-ray imaging: Proof of concept.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)·2020
Same author

Cone-beam CT dose and imaging performance evaluation with a modular, multipurpose phantom.

Medical physics·2019
Same author

Evaluation of the BreastSimulator software platform for breast tomography.

Physics in medicine and biology·2017
Same author

Spectrum of bone marrow morphologic findings in hepatitis C patients with and without prior liver transplantation.

International journal of laboratory hematology·2016
Same author

Radiological Protection in Cone Beam Computed Tomography (CBCT). ICRP Publication 129.

Annals of the ICRP·2015
Same author

Simulated lesion, human observer performance comparison between thin-section dedicated breast CT images versus computed thick-section simulated projection images of the breast.

Physics in medicine and biology·2015

Area of Science:

  • Radiology
  • Medical Imaging
  • Radiation Dosimetry

Background:

  • Mammography is the current standard for breast cancer screening.
  • Limitations exist in mammography, particularly for dense breast tissue.
  • Advancements in imaging technology are sought to improve diagnostic accuracy and patient outcomes.

Purpose of the Study:

  • To assess the feasibility of dedicated breast computed tomography (CT).
  • To evaluate radiation dose and image quality of breast CT.
  • To compare breast CT parameters with mammography standards.

Main Methods:

  • Monte Carlo simulations estimated average glandular dose (AGD).
  • Abdominal CT parameters served as a benchmark for breast CT dose calculation.
  • Image noise was measured using a phantom at varying kilovoltage peak (kVp) and milliampere-seconds (mAs).

Related Experiment Videos

  • A cadaveric breast was imaged to simulate breast CT acquisition geometry.

    • Main Results:

    • Breast CT radiation dose at 80 kVp was comparable to mammography for 5-cm breasts.
    • For thicker breasts, breast CT dose was one-third lower than mammography.
    • Breast CT yielded significantly lower maximum radiation doses (5.4 mGy) compared to mammography (20.0 mGy) for a typical 5-cm breast.
    • Images of an 8-cm cadaveric breast from CT (AGD 6.3 mGy) were subjectively superior to mammograms (AGD 10.1 mGy).

    Conclusions:

    • Breast CT offers high signal-to-noise ratio and low anatomic noise images.
    • Achievable radiation dose levels are comparable to mammography.
    • Further research into dedicated breast CT is warranted for breast cancer screening and diagnosis.