Novel bicyclic lactam inhibitors of thrombin: potency and selectivity optimization through P1 residues

S Lévesque1, Y St-Denis, B Bachand

  • 1Shire BioChem Inc., 275 Armand-Frappier Blvd., Laval, H7V 4A7, Québec, Canada. slevesque@ca.shire.com