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Predictors of radial artery patency for coronary bypass operations
1Department of Cardiovascular Diseases, Catholic University School of Medicine, and Clinica Alemana, Santiago, Chile. smoran@med.puc.cl
Insights
Coronary artery bypass grafting using radial artery grafts shows improved patency when native arteries have significant stenosis. Diltiazem did not affect graft patency rates in this study.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Vascular Grafting
Background:
- Limited data on angiographic predictors for radial artery patency in coronary bypass grafting.
- Unclear benefit of calcium antagonists on graft outcomes.
Purpose of the Study:
- Identify angiographic predictors of radial artery graft patency.
- Evaluate the impact of diltiazem on graft patency.
Main Methods:
- Studied 115 patients undergoing myocardial revascularization with radial artery, internal mammary, and vein grafts.
- Quantitative angiography analyzed graft patency at 1 year post-surgery.
- Compared outcomes between patients receiving diltiazem and those who did not.
Main Results:
- Radial artery graft patency was 80% at 30-month follow-up.
- Higher native coronary artery stenosis (>=70%) correlated with significantly better radial graft patency (92%).
- No significant difference in clinical or angiographic outcomes with diltiazem use.
Conclusions:
- Native coronary artery stenosis is a key predictor of radial artery graft patency.
- Diltiazem does not appear to influence radial artery graft patency.
Background:
Few data exist regarding angiographic predictors of radial artery patency for coronary bypass grafting, and the benefit of calcium antagonists is not clear.
Methods:
One hundred fifteen patients were studied who had myocardial revascularization with the radial artery plus internal mammary and vein grafts with 3.5 +/- 1.1 grafts per patient. Sixty-three patients received diltiazem and 52 patients did not. Base line and follow-up angiographies were analyzed 1 year postoperatively in 50 of these patients with a quantitative computerized method.
Results:
One hundred fourteen patients survived and were followed for 30.1 +/- 12.6 months. Patency for mammary grafts was 100%, for radial grafts it was 80%, and for saphenous vein grafts it was 68%. Patent radial artery grafts had significantly greater degree of stenosis in the native vessels than occluded grafts (73% +/- 14% vs 40% +/- 24%), (p = 0.0007; confidence interval = 95%). Radial artery patency increased to 92% when arteries with 70% or more stenosis were considered. No differences were observed for clinical and angiographic end points in the patients that received diltiazem compared with the rest who had not.
Conclusions:
The degree of stenosis in the native coronary artery significantly influences the patency rate of radial artery grafts, independent of diltiazem.
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