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Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
Published on: July 18, 2017
Diagnostic Investigation of Pyelonephritis
Kambiz Zandi-Nejad1, Patricia D. Brown
1Division of Infectious Diseases, Department of Internal Medicine, Wayne State University School of Medicine, Harper Hospital, 4 Brush Center, 3990 John R, Detroit, MI 48201, USA. pbrown@intmed.wayne.edu
Abstract:
Urinary tract infections are common, especially among women, and cause significant morbidity. While prognosis is probably more dependent on whether or not an episode of urinary tract infection is complicated (ie, associated with functional, metabolic, or anatomic abnormalities of the urinary tract) or uncomplicated, anatomic localization of infection has important implications for therapy. Pyelonephritis is difficult to diagnose with a high degree of accuracy based on clinical findings alone. Radiologic imaging plays an important role in the diagnosis and management of selected patients. Noninvasive and inexpensive methods to allow accurate localization of infection are needed.
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