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[Association between ischemic heart disease and peptic ulcer. A case-control study]

J Baena Díez1, D López Gosp, M De La Poza Abad

  • 1Area Básica de Salud, Barcelona, Spain. jbaenad@meditex.es

Gastroenterologia Y Hepatologia
|November 28, 2001
PubMed

Insights

Patients with ischemic heart disease (IHD) have a significantly higher risk of developing peptic ulcers (PU). This study found a 77% increased odds of PU in IHD patients, particularly duodenal ulcers.

Area of Science:

  • Cardiology
  • Gastroenterology
  • Epidemiology

Context:

  • Ischemic heart disease (IHD) is a prevalent condition.
  • Peptic ulcer (PU) disease affects a significant portion of the population.
  • The relationship between IHD and PU risk requires further investigation.

Purpose:

  • To investigate the association between ischemic heart disease (IHD) and the risk of developing peptic ulcers (PU).

Summary:

  • A case-control study involving 310 IHD patients and 310 controls was conducted.
  • Data from clinical histories revealed a higher incidence of PU in the IHD group (18.7% vs. 12.3%).
  • Adjusted analysis showed an increased odds ratio (OR) of 1.77 for PU in IHD patients, primarily driven by duodenal ulcers (OR 2.22).

Impact:

  • Findings suggest IHD is an independent risk factor for peptic ulcer development.
  • Highlights the need for increased vigilance for PU in patients with IHD.
  • Informs clinical practice regarding gastrointestinal health in cardiac patients.
Abstract

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