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Thrombophilia: what's a practitioner to do?
B G Macik1, J H Rand, B A Konkle
1Division of Hematology/Oncology, University of Virginia, Charlottesville 22908-0747, USA.
Hematology. American Society of Hematology. Education Program
|November 28, 2001
Summary
This paper updates thrombophilia management, focusing on antiphospholipid syndrome, women's health considerations, and new warfarin self-management options using home monitoring devices.
Area of Science:
- Hematology
- Thrombosis Management
Background:
- Thrombophilia management is evolving with new disorders and clinical insights.
- Key challenges include diagnosing and treating antiphospholipid syndrome and managing women with thrombophilia.
Purpose of the Study:
- To provide updated guidance on managing antiphospholipid syndrome.
- To review risks associated with hormonal therapy and pregnancy in women with thrombophilia.
- To introduce novel approaches to warfarin management through home monitoring.
Main Methods:
- Review of current diagnostic and treatment strategies for antiphospholipid syndrome.
- Analysis of data regarding hormonal therapy and pregnancy risks in women with thrombophilia.
- Evaluation of home prothrombin time (PT) monitoring instruments for warfarin self-management.
Main Results:
- Updated diagnostic and treatment strategies for antiphospholipid syndrome.
- Comprehensive review of risks for women with thrombophilia undergoing hormonal therapy or pregnancy.
- Emerging evidence supports self-testing and self-management of warfarin therapy.
Conclusions:
- Optimized management of antiphospholipid syndrome is achievable with current understanding.
- Informed counseling on hormonal therapy and pregnancy is crucial for women with thrombophilia.
- Home-based warfarin monitoring offers a reliable alternative to traditional care.