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Current topics on immunoadsorption therapy.

S Nakaji1

  • 1Medical Products Development Department, Kuraray Co., Ltd., Kurashiki, Japan. Shuhei_Nakaji@kuraray.co.jp

Therapeutic Apheresis : Official Journal of the International Society for Apheresis and the Japanese Society for Apheresis
|November 29, 2001
PubMed
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Immunoadsorption therapy is increasingly used for autoimmune diseases. New peptide columns offer potential for targeted removal of pathogenic substances, improving treatment specificity.

Area of Science:

  • Medical Science
  • Biotechnology

Background:

  • Immunoadsorption therapy is gaining prominence for treating autoimmune diseases.
  • The availability of diverse immunoadsorption columns for clinical use is expanding.

Purpose of the Study:

  • To review clinically available immunoadsorption columns.
  • To describe peptide-based immunoadsorption columns and their potential.

Main Methods:

  • Review of existing immunoadsorption columns (Immusorba TR/PH, Selesorb, Prosorba, Immunosorba, Ig-Therasorb, Medisorba MG).
  • Description of peptide columns utilizing immobilized peptides as ligands.

Main Results:

  • Several immunoadsorption columns for plasma perfusion and direct hemoperfusion are currently available.

Related Experiment Videos

  • Peptide columns demonstrate potential for specific pathogen removal through tailored peptide design.

    • Conclusions:

    • The increasing number of immunoadsorption columns supports their growing role in autoimmune disease management.
    • Peptide columns represent a promising advancement for highly specific immunoadsorption therapies.