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Structure of SL4 RNA from the HIV-1 packaging signal

D J Kerwood1, M J Cavaluzzi, P N Borer

  • 1Department of Chemistry, Graduate Program in Structural Biology, Biochemistry, and Biophysics, Syracuse University, Syracuse, New York 13244-4100, USA.

Biochemistry
|November 29, 2001
PubMed
Summary

This study details the NMR structure of HIV-1 stem-loop 4 (SL4), revealing a GAGA tetraloop conformation and unique G.U base pairing. Enhanced mobility in the 5' stem region impacts hairpin stability.

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