Red cell esterase-D polymorphism in the population of Tuscany

Esterase-D phenotypes were determined in a population sample of Tuscany, Italy. The observed frequencies of the three alleles are: EsD1 = 0.856, EsD2 = 0.143 and EsD3 = 0.001. Studies of the pedigree of the propositus's EsD 3--1 family and mother-child combinations confirm an autosomal co-dominant inheritance.