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The aetiology of idiopathic Parkinson's disease
D B Ramsden1, R B Parsons, S L Ho
1Department of Medicine, Division of Medical Science, University of Birmingham, Queen Elizabeth Hospital, Birmingham B15 2TH, UK. D.B.Ramsden@bham.ac.uk
Molecular Pathology : MP
|November 29, 2001
Abstract:
Agents potentially involved in the aetiology of idiopathic Parkinson's disease are discussed. These include factors regulating dopaminergic neurogenesis (Nurr 1, Ptx-3, and Lmx1b) and related proteins, together with genes involved in familial Parkinson's disease (alpha synuclein, parkin, and ubiquitin carboxy terminal hydroxylase L1), and endogenous and environmental agents.