Pharmacotherapy in smoking cessation

The authors reviewed literature on nicotine replacement therapy and bupropion in smoking cessation. Nicotine replacement therapy increases the quit rate in smoking cessation; however, its efficacy is influenced by numerous factors. Bupropion, particularly combined with nicotine replacement therapy, reaches even higher efficacy. Behavioural therapy as well as individualized approach during the cessation process are beneficial. Beside from this, these agents help to avoid excessive weight gain after quitting. If properly used, they have minimal side effects, and, if not contraindicated, they should be included into standard smoking cessation programs. (Ref. 74.)