Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Thyroid autoimmunity and infertility.

G Grassi1, A Balsamo, C Ansaldi

  • 1Department of Obstetrics and Gynecology, University of Torino, Torino, Italy.

Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology
|December 1, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Management of andrological disorders from childhood and adolescence to transition age: guidelines from the Italian Society of Andrology and Sexual Medicine (SIAMS) in collaboration with the Italian Society for Pediatric Endocrinology and Diabetology (SIEDP) - part-2.

Journal of endocrinological investigation·2026
Same author

A novel machine-learning framework based on early embryo morphokinetics identifies a feature signature associated with blastocyst development.

Journal of ovarian research·2024
Same author

The importance of rotation to teach secure half-hitch sequences in surgery.

Facts, views & vision in ObGyn·2023
Same author

Search for Subsolar-Mass Binaries in the First Half of Advanced LIGO's and Advanced Virgo's Third Observing Run.

Physical review letters·2022
Same author

The 2016 Revision of ISO 1 - Standard Reference Temperature for the Specification of Geometrical and Dimensional Properties.

Journal of research of the National Institute of Standards and Technology·2021
Same author

Constraints on Cosmic Strings Using Data from the Third Advanced LIGO-Virgo Observing Run.

Physical review letters·2021
Same journal

European society of gynecology (ESG) position paper on the proposed terminology change from PCOS to PMOS.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology·2026
Same journal

Peripheral precocious puberty with unilateral ovarian agenesis in early childhood: a case report and review of literature.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology·2026
Same journal

Transdermal versus oral hormone replacement therapy and bone mass density in Turner syndrome patients: a pilot study.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology·2026
Same journal

Elevated ESR2 and BRCA1 gene expression in adenomyosis associated with endometrial cancer: a pilot study.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology·2026
Same journal

Progestin therapy in premenopausal women with incidental meningioma-a narrative review and recommendations for women's health specialists.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology·2026
Same journal

Inter-rater reliability and clinical utility of the modified ferriman-gallwey scale in routine practice.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology·2026
See all related articles

Thyroid autoimmunity is common in infertile women, but thyroid autoantibodies alone do not impact pregnancy chances. Thyroid abnormalities combined with ovulatory dysfunction significantly increase infertility duration.

Area of Science:

  • Endocrinology
  • Reproductive Medicine
  • Immunology

Background:

  • Thyroid autoimmunity is increasingly recognized as a potential factor in infertility.
  • The relationship between thyroid dysfunction, autoantibodies, and fertility outcomes requires further elucidation.

Purpose of the Study:

  • To determine the prevalence of thyroid autoimmunity in infertile women.
  • To assess the association between thyroid autoantibodies and non-organ-specific autoantibodies.
  • To investigate the impact of thyroid dysfunction on pregnancy rates in infertile couples.

Main Methods:

  • Assayed serum levels of TSH, free thyroxine, and thyroid autoantibodies (microsomal and thyroglobulin) in 149 infertile women.
  • Performed thyroid ultrasound and tested for non-organ-specific autoantibodies in patients with abnormal thyroid function or antibodies.

Related Experiment Videos

  • Compared infertility duration across groups: normal thyroid, thyroid abnormalities, and euthyroid with thyroid autoantibodies.

    • Main Results:

    • Thyroid abnormalities were found in 20.1% of infertile women; thyroid autoantibodies prevalence was 17.4%.
    • A weak association was observed between thyroid autoantibodies and non-organ-specific autoantibodies.
    • Only women with thyroid abnormalities and ovulatory dysfunction showed a significantly longer infertility duration compared to controls.

    Conclusions:

    • While thyroid autoimmunity is prevalent in infertile women, the mere presence of thyroid autoantibodies does not diminish pregnancy chances.
    • Thyroid abnormalities coupled with ovulatory dysfunction represent a significant factor contributing to prolonged infertility.