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Related Experiment Videos

Bilateral wrist dislocation in trisomy 21: a case report.

W M Jan1, J G Kennedy, F E Dowling

  • 1Our Lady's Hospital for Sick Children, Crumlin, Ireland.

Journal of Pediatric Orthopedics. Part B
|December 1, 2001
PubMed
Summary

Ligamentous laxity is common in Down's syndrome. This study reports the first documented cases of non-traumatic wrist dislocations in individuals with Trisomy 21, highlighting a previously unrecognized manifestation of joint instability.

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Area of Science:

  • Orthopedics
  • Genetics
  • Rheumatology

Background:

  • Ligamentous laxity and joint instability are well-documented features associated with Trisomy 21 (Down's syndrome).
  • Previous literature extensively reports various joint instabilities, including atlanto-axial, patellar, and carpal instability in this population.

Observation:

  • This study observed non-traumatic wrist dislocations in individuals diagnosed with Trisomy 21.
  • These dislocations were noted as either unilateral or bilateral, representing a novel clinical presentation.

Findings:

  • The findings indicate that non-traumatic wrist dislocation is a previously unreported complication in Trisomy 21.
  • This condition has not been previously described in the English literature for Trisomy 21 or any other condition.

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Implications:

  • These findings suggest that wrist instability should be considered in the differential diagnosis of joint issues in Trisomy 21.
  • Further research is warranted to understand the underlying mechanisms and prevalence of non-traumatic wrist dislocations in Trisomy 21.