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Reconstructive surgery using an artificial dermis (Integra): results with 39 grafts.

E Dantzer1, F M Braye

  • 1Centre de Traitement des Brûlés, Hôpital Léon Bérard, Hyeres, France.

British Journal of Plastic Surgery
|December 1, 2001
PubMed
Summary

Integra, a dermal regeneration template, shows promise in reconstructive surgery beyond acute burns. This study found good to average results in most patients, offering a viable alternative for skin reconstruction.

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Area of Science:

  • Regenerative Medicine
  • Plastic and Reconstructive Surgery

Background:

  • Integra is a dermal regeneration template initially developed for acute burn coverage.
  • It functions as a scaffold for dermal reconstruction, requiring an epidermal graft overlay.

Purpose of the Study:

  • To evaluate the efficacy of Integra in reconstructive surgery for burn scars and other defects.
  • To assess functional and aesthetic outcomes of Integra grafting in a diverse patient cohort.

Main Methods:

  • A series of 31 patients (39 sites) underwent Integra grafting for reconstructive surgery.
  • Average grafted area was 267 cm(2); follow-up ranged from 0.5 to 4 years.

Main Results:

  • Good results were achieved in 28 cases, average in six, and poor in three.

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  • Complications included silicone detachment, graft failure, and hematoma in nine cases.

    • Conclusions:

    • Integra offers advantages like immediate availability, large quantities, and good cosmetic results.
    • It presents a viable alternative to traditional skin grafting, expansion, and flaps in reconstructive surgery.