Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Implementing randomization procedures in the asthma clinical research network.

S J Kunselman1, T J Armstrong, T B Britton

  • 1Department of Health Evaluation Sciences, College of Medicine, Pennsylvania State University, Hershey, PA 17033-0855, USA.

Controlled Clinical Trials
|December 1, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spherical-angular dark field imaging and sensitive microstructural phase clustering with unsupervised machine learning.

Ultramicroscopy·2020
Same author

Advancing characterisation with statistics from correlative electron diffraction and X-ray spectroscopy, in the scanning electron microscope.

Ultramicroscopy·2020
Same author

Indexing electron backscatter diffraction patterns with a refined template matching approach.

Ultramicroscopy·2019
Same author

Normal force distribution and posture of a hand pressing on a flat surface.

Journal of biomechanics·2018
Same author

Using transmission Kikuchi diffraction to characterise α variants in an α+β titanium alloy.

Journal of microscopy·2017
Same author

A strategy for evaluating occupational risk factors of musculoskeletal disorders.

Journal of occupational rehabilitation·2013
Same journal

On the generation and ownership of alpha in medical studies.

Controlled clinical trials·2004
Same journal

An analysis of the effect of funding source in randomized clinical trials of second generation antipsychotics for the treatment of schizophrenia.

Controlled clinical trials·2004
Same journal

Symptom recording in a randomised clinical trial: paper diaries vs. electronic or telephone data capture.

Controlled clinical trials·2004
Same journal

Statistical comparison of random allocation methods in cancer clinical trials.

Controlled clinical trials·2004
Same journal

Analyzing bronchodilation with emphasis on disease type, age and sex.

Controlled clinical trials·2004
Same journal

Geographic variability in patient characteristics, treatment and outcome in an International Trial of Magnesium in acute myocardial infarction.

Controlled clinical trials·2004
See all related articles

Proper randomization procedures are crucial for successful clinical trials. This paper details the registration and randomization methods used in the Asthma Clinical Research Network

Area of Science:

  • Clinical Trials Methodology
  • Respiratory Medicine
  • Biostatistics

Background:

  • Randomization is essential for the integrity of controlled clinical trials.
  • Effective randomization requires meticulously planned procedures implemented before trial commencement.

Purpose of the Study:

  • To describe the registration and randomization processes for the initial four trials within the Asthma Clinical Research Network.
  • To provide a procedural framework for future clinical trial design and implementation.

Main Methods:

  • Detailed account of registration procedures.
  • In-depth explanation of randomization techniques.
  • Focus on the practical application within the Asthma Clinical Research Network's first four trials.

Related Experiment Videos

Main Results:

  • Successful implementation of defined registration and randomization protocols.
  • Established a robust procedural framework for multi-center asthma research.
  • Ensured unbiased participant allocation across treatment arms.

Conclusions:

  • Well-defined randomization and registration procedures are critical for valid clinical trial outcomes.
  • The documented procedures provide a valuable model for respiratory clinical research networks.
  • Adherence to rigorous protocols maximizes the scientific value of clinical trial data.