Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Quality control within the Asthma Clinical Research Network.

R J Martin1, D K Kephart, A M Dyer

  • 1National Jewish Medical and Research Center, Denver, CO 80206, USA. martinr@njc.org

Controlled Clinical Trials
|December 1, 2001
PubMed
Summary

Strict quality control measures in multicenter asthma research are crucial for minimizing data variance. The Asthma Clinical Research Network (ACRN) implemented rigorous protocols for procedures, personnel, and evaluations to ensure reliable clinical investigation results.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Safe discharge on the second postoperative day after major colorectal surgery: a decision-making strategy based on quantitative serological data.

Techniques in coloproctology·2026
Same author

Voices from the Bench: Focus Group Insights on Shared Research Resource Sustainability Amid Federal Policy Shifts.

Journal of biomolecular techniques : JBT·2026
Same author

Defining Standard Data Reporting in Pelvic Exenterations for Non-Rectal Cancers: A Systematic Review of Current Data Reporting.

Cancers·2025
Same author

Proteomic, miRNA and bacterial biomarker patterns in atopic dermatitis patients and their course upon anti-IL-4Rα therapy.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024
Same author

Paradoxical effects of cigarette smoke and COPD on SARS-CoV-2 infection and disease.

BMC pulmonary medicine·2021
Same author

Anaphylaxis to vaccination and polyethylene glycol: a perspective from the European Anaphylaxis Registry.

Journal of the European Academy of Dermatology and Venereology : JEADV·2021

Area of Science:

  • Clinical research methodology
  • Multicenter study design
  • Quality assurance in healthcare

Background:

  • Multicenter clinical investigations require robust quality control and assurance.
  • Existing investigations often implement these factors minimally.
  • Variability between research centers can compromise data integrity.

Purpose of the Study:

  • To detail the quality control strategies implemented by the Asthma Clinical Research Network (ACRN).
  • To ensure high-quality investigatory results with minimal inter-center variance.
  • To provide examples of ACRN's quality control procedures.

Main Methods:

  • Establishment of strict, written quality control criteria.
  • Continuous oversight and review of all protocols.

Related Experiment Videos

  • Standardized training and certification for study personnel.
  • Regular site visit evaluations.
  • Standardized procedures for bronchoscopy and sputum induction.

    • Main Results:

    • Implementation of comprehensive quality control across multiple facets of the investigation.
    • Demonstration of adherence to strict protocols for clinic procedures and equipment.
    • Successful training and certification of all study personnel.
    • Consistent application of evaluation procedures for bronchoscopy and sputum induction.

    Conclusions:

    • Rigorous quality control is essential for multicenter clinical investigations like those conducted by ACRN.
    • Standardized criteria and continuous oversight effectively minimize inter-center variance.
    • The ACRN model provides a framework for ensuring reliable and high-quality research outcomes in asthma studies.