Related Experiment Video
Updated: Oct 3, 2026

Assessment of Antibody-based Drugs Effects on Murine Bone Marrow and Peritoneal Macrophage Activation
Published on: December 26, 2017
[Inhibitors of absorption as anti-obesity drugs]
1First Department of Internal Medicine, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8662, Japan.
Abstract:
There are two types of anti-obesity agents which are classified as inhibitors of absorption: inhibitors of lipid and carbohydrate absorption. Inhibitors of lipid absorption consist of lipase inhibitor (orlistat, Nomma Herb's extract (CT-II) and fat substitute (olestra, sucrose polyester). Orlistat is now available as an anti-obesity drug in the USA and Europe. CT-II may be useful as a functional diet. Application of fat substitute is still limited in snack food. As for inhibitors of carbohydrate absorption, alpha-glucosidase inhibitors are now available as anti-diabetic drugs. To develop these agents for anti-obesity drug, solution of adverse effects on the gastrointestinal tract are necessary.
Related Concept Videos
Oral Hypoglycemic Agents: α-Glucosidase Inhibitors
Acarbose and miglitol are typically...
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
Factors Influencing Drug Absorption: Disease States and Pharmacology
Substances such as alcohol and specific drugs, including antineoplastics, can also negatively impact drug absorption. For instance,...
Drug Absorption: Factors Affecting GI Absorption
In...
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion
Drugs Affecting GI Tract Motility: Adsorbents as Antidiarrheal Agents
Adsorbents...